Tạp chí Y học Thành phố Hồ Chí Minh, 18(6):326. DOI
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Lê Thị Kim Hương*, Nguyễn Đỗ Phúc**
ANTIBIOTIC SUSCEPTIBILITY OF BACTERIAL STRAINS ISOLATED FROM PATIENTS
WITH INFECTIONS AT REGIONAL GENERAL HOSPITAL OF THU DUC DISTRICT
Le Thi Kim Huong, Nguyen Do Phuc
* Y Hoc TP. Ho Chi Minh * Vol. 18 - Supplement of No 6- 2014: 326 – 331
Background:
Recently, single- and multiple-drug resistant bacteria have been highly
detected. Bacteria are resistant not only to available antibiotics but
also to new antibiotics. On the other hand, bacteria that are not
pathogenic but resistant to single or multiple drugs are the reservoir
of resistance genes possible to be transferred to other pathogenic
bacteria.
Objectives:
To investigate bacteria occurred in blood, sputum, secretion, urine
specimens obtained from infected patients and their antibiotic
susceptibilities.
Methods:
A cross-sectional study design was conducted with the aim of bacterial
isolation, identification, and antibiotic susceptibility testing in
blood, sputum, secretion, urine specimens collected from infected
patients treated at Regional General Hospital of Thu Duc District from
January to June 2013.
Result:
Gram negative bacteria including Acinetobacter (32.35%), Klebsiella
(22.55%), Pseudomonas (10.19%), and Escherichia (8%) were dominant
(73.09%) among the isolations. Gram positive bacteria composing of
26.91% total isolations included Staphylococcus (19.64%), and
Streptococcus (7.27%). Acinetobacter spp., K. ozaenae, K. pneumoniae, E.
coli, P. aeruginosa and S. aureus were the most prevalent isolations
from blood, sputum, secretion, urine specimens among 266 patients. These
bacteria were resistant to 14 antibiotics as antibiotic susceptibility
tests were performed, except that K. pneumoniae was unsusceptible to Im.
The
highest resistance rates of isolated bacterial strains: Bt resistant K.
ozaenae (100%), Ci resistant K. pneumoniae and E. coli (83.3% and 88.8
%, respectively), Cl resistant P. aeruginosa and S. aureus (100% and
94.7%, respectively), and Ct resistant Acinetobacter spp. (92.3%).
Conclusion: Most of bacteria were highly resistant to multiple antibiotics.
Keywords: Bacteria, resistance, infection.